{"id":1097,"date":"2020-07-14T12:20:51","date_gmt":"2020-07-14T09:20:51","guid":{"rendered":"https:\/\/herbalaid.gr\/?page_id=1097"},"modified":"2020-09-24T13:31:06","modified_gmt":"2020-09-24T10:31:06","slug":"project-structure","status":"publish","type":"page","link":"https:\/\/herbalaid.gr\/?page_id=1097","title":{"rendered":"\u039c\u0395\u0398\u039f\u0394\u039f\u039b\u039f\u0393\u0399\u0391 \u03a5\u039b\u039f\u03a0\u039f\u0399\u0397\u03a3\u0397\u03a3"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row full_width=&#8221;container-null&#8221;][vc_column agro_disable_column=&#8221;yes&#8221;]<div id=\"hero\" class=\"nt-shortcode-hero jarallax section_6a06f169dc4da vc_custom_1600943465290 \" data-speed=\"0.7\" data-img-position=\"50% 80%\" data-res-css=\"          \"><div class=\"container\"><div class=\"row\"><div class=\"col-12 col-lg-7\"><h1 class=\"__title\"><span>\u03a4\u039f \u0395\u03a1\u0393\u039f<\/span> \u039c\u0395\u0398\u039f\u0394\u039f\u039b\u039f\u0393\u0399\u0391 \u03a5\u039b\u039f\u03a0\u039f\u0399\u0397\u03a3\u0397\u03a3<\/h1><p class=\"nt-hero-desc\">\u0391\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ad\u03c1\u03b3\u03bf\u03c5 \u03c9\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03c6\u03c5\u03c3\u03b9\u03ba\u03cc \u03b1\u03bd\u03c4\u03b9\u03ba\u03b5\u03af\u03bc\u03b5\u03bd\u03bf \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03b5\u03c0\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2.<\/p><div class=\"shortcode-page-breadcrumbs breadcrumb\"><div class=\"nt-breadcrumbs\"><ul class=\"nt-breadcrumbs-list\"><li class=\"bitem\"><span><a class=\"breadcrumbs__link\" href=\"https:\/\/herbalaid.gr\/\"><span>Home<\/span><\/a><\/span><\/li><\/ul><\/div><\/div><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=&#8221;container-null&#8221;][vc_column agro_disable_column=&#8221;yes&#8221;]<div class=\"section section--no-pb about--1 md-hide-bg item_6a06f169dc790\" data-res-css=\"              \"><div class=\"container\"><div class=\"section-heading\"><h2 class=\"__title\">\u039c\u03b5\u03b8\u03bf\u03b4\u03bf\u03bb\u03bf\u03b3\u03b9\u03b1 \u03a5\u03bb\u03bf\u03c0\u03bf\u03b9\u03b7\u03c3\u03b7\u03c2 <span>\u0395\u03c1\u03b3\u03bf\u03c5<\/span><\/h2><\/div><div class=\"row\"><div class=\"col-12 col-lg-6 col-xl-8\">\n<p style=\"text-align: justify;\"><strong>1.<\/strong> <strong>\u03a0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>1.1<\/strong>. In vitro \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd. \u0398\u03b1 \u03bc\u03b5\u03bb\u03b5\u03c4\u03b7\u03b8\u03b5\u03af \u03c3\u03b5 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 Alzheimer\u2019s (\u03c0\u03c1\u03c9\u03c4\u03bf\u03b3\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03bb\u03bb\u03b9\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2 \u03b5\u03bc\u03b2\u03c1\u03c5\u03b9\u03ba\u03ce\u03bd \u03bd\u03b5\u03c5\u03c1\u03ce\u03bd\u03c9\u03bd \u03b9\u03c0\u03c0\u03bf\u03ba\u03ac\u03bc\u03c0\u03bf\u03c5 \u03bc\u03c5\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b5\u03c2 \u03bd\u03b5\u03c5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c3\u03b5\u03b9\u03c1\u03ad\u03c2), \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd [Salvia lavandulifolia (\u03c6\u03b1\u03c3\u03ba\u03cc\u03bc\u03b7\u03bb\u03bf), Thymus serpyllum \u03ae Saturejia hortensis (\u03b8\u03c5\u03bc\u03ac\u03c1\u03b9), Ocimum Basilicum (\u03b2\u03b1\u03c3\u03b9\u03bb\u03b9\u03ba\u03cc\u03c2), Aloe vera (\u03b1\u03bb\u03cc\u03b7), Crocus sativus (\u03ba\u03c1\u03cc\u03ba\u03bf\u03c2), Sideritis raeseri (\u03c4\u03c3\u03ac\u03b9 \u03b2\u03bf\u03c5\u03bd\u03bf\u03cd), Curcuma domestica \u03ae Curcuma longa (\u03ba\u03bf\u03c5\u03c1\u03ba\u03bf\u03c5\u03bc\u03ac\u03c2), Rosmarinus officinalis (\u03b4\u03b5\u03bd\u03b4\u03c1\u03bf\u03bb\u03af\u03b2\u03b1\u03bd\u03bf), Olea europaea (\u03c6\u03cd\u03bb\u03bb\u03b1 \u03b5\u03bb\u03b9\u03ac\u03c2, \u03b1\u03b3\u03bf\u03c5\u03c1\u03ad\u03bb\u03b1\u03b9\u03bf)] \u03ba\u03b1\u03b9 \u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b1\u03c5\u03c4\u03ce\u03bd.<br \/>\n\u0391\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7:<br \/>\n(\u03b1) \u03c3\u03b5 \u03bd\u03b5\u03c5\u03c1\u03ce\u03bd\u03b5\u03c2, \u03c4\u03b7\u03c2 \u03ba\u03c5\u03c4\u03bf\u03c4\u03bf\u03be\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03bf\u03bb\u03b9\u03b3\u03bf\u03bc\u03b5\u03c1\u03ce\u03bd \u0391\u03b242<br \/>\n(\u03b2) \u03c3\u03b5 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03b9\u03bd\u03b7 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03c3\u03b5\u03b9\u03c1\u03ac \u03bd\u03b5\u03c5\u03c1\u03bf\u03b2\u03bb\u03b1\u03c3\u03c4\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2, SH-SY5Y<br \/>\n1. \u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03cc \u03c3\u03c4\u03c1\u03b5\u03c2<br \/>\n2. \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03bf\u03ba\u03b1\u03b4\u03bf\u03ca\u03ba\u03bf\u03cd \u03bf\u03be\u03ad\u03c9\u03c2 (\u039f\u0391)<br \/>\n3. \u03c5\u03c0\u03b5\u03c1\u03c6\u03c9\u03c3\u03c6\u03bf\u03c1\u03c5\u03bb\u03af\u03c9\u03c3\u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 Tau<br \/>\n(\u03b3) \u03c3\u03b5 \u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ae \u03c3\u03b5\u03b9\u03c1\u03ac 7PA2 (CHO-APPVal717Phe), \u03c4\u03b7\u03c2 \u03ad\u03ba\u03ba\u03c1\u03b9\u03c3\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03bf\u03cd \u03c0\u03b1\u03b8\u03bf\u03b3\u03cc\u03bd\u03c9\u03bd \u03bf\u03bb\u03b9\u03b3\u03bf\u03bc\u03b5\u03c1\u03ce\u03bd \u0391\u03b2<\/p>\n<p style=\"text-align: justify;\"><strong>1.2.<\/strong> In vivo \u03b6\u03c9\u03b9\u03ba\u03cc \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03bf \u03bd\u03cc\u03c3\u03bf\u03c5 Alzheimer\u2019s \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b4\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd.<br \/>\nH \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c5\u03c0\u03cc \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd \u03b8\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ce\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1 \u03b5\u03c5\u03c1\u03ad\u03c9\u03c2 \u03bc\u03b5\u03bb\u03b5\u03c4\u03b7\u03bc\u03ad\u03bd\u03bf \u03b6\u03c9\u03b9\u03ba\u03cc \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03bf \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 Alzheimer\u2019s, \u03c4\u03bf \u03c3\u03c4\u03ad\u03bb\u03b5\u03c7\u03bf\u03c2 \u03bc\u03c5\u03ce\u03bd 3xTg [7]. \u03a0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ac \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03b4\u03b9\u03b1\u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03bf\u03cd\u03c2 \u03bc\u03cd\u03b5\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bf\u03c0\u03bf\u03af\u03bf\u03c5\u03c2 \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03b9\u03c3\u03b1\u03c7\u03b8\u03b5\u03af \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03b1\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ad\u03c2 \u03c4\u03c9\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd APP (\u03c0\u03c1\u03cc\u03b4\u03c1\u03bf\u03bc\u03b7 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2), MAPT (\u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7 Tau) \u03ba\u03b1\u03b9 PSEN1 (\u03c0\u03c1\u03b5\u03c3\u03b5\u03bd\u03b9\u03bb\u03af\u03bd\u03b7 1). \u039f\u03b9 \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03b9 APPSwe, \u039c\u0391\u03a1\u03a4\u03a1301L \u03ba\u03b1\u03b9 PSEN1M146V \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5. T\u03bf \u03b6\u03c9\u03b9\u03ba\u03cc \u03b1\u03c5\u03c4\u03cc \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03bf \u03ad\u03c7\u03b5\u03b9 \u03b5\u03b9\u03c3\u03b1\u03c7\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u0391\u03bc\u03b5\u03c1\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c0\u03c4\u03c5\u03c7\u03b8\u03b5\u03af \u03c3\u03c4\u03b7\u03bd \u0395\u03bb\u03bb\u03ac\u03b4\u03b1 \u03c5\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b2\u03bb\u03b5\u03c8\u03b7 \u03c4\u03b7\u03c2 \u03ba. \u03a7\u03c1\u03b9\u03c3\u03c4\u03af\u03bd\u03b1\u03c2 \u0394\u03ac\u03bb\u03bb\u03b1, \u03ba\u03b1\u03b9 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03b9 \u03c3\u03b5 \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 12 \u03bc\u03b7\u03bd\u03ce\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac, \u03cc\u03c0\u03c9\u03c2 \u03b5\u03be\u03c9\u03ba\u03c5\u03c4\u03c4\u03b1\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c0\u03bb\u03ac\u03ba\u03b5\u03c2 A\u03b2 \u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bc\u03c6\u03b1\u03bd\u03ae \u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 Tau.<\/p>\n<p style=\"text-align: justify;\"><strong>2.<\/strong> <strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7<\/strong><br \/>\n\u0394\u03b9\u03b5\u03c1\u03b5\u03cd\u03bd\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2 \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd \u03c3\u03c4\u03b7 \u03bd\u03cc\u03c3\u03bf Alzheimer\u2019s.<br \/>\n\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u0389\u03c0\u03b9\u03b1 \u039d\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03ba\u03b1\u03b9 \u03bd\u03cc\u03c3\u03bf Alzheimer\u2019s \u03b8\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03b7 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd. \u03a0\u03b9\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1, \u03c3\u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03b8\u03b1 \u03c7\u03bf\u03c1\u03b7\u03b3\u03b7\u03b8\u03bf\u03cd\u03bd \u03c4\u03b1 \u03b5\u03ba\u03c7\u03c5\u03bb\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b2\u03bf\u03c4\u03ac\u03bd\u03c9\u03bd, \u03c4\u03b1 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b8\u03b1 \u03b4\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 in vitro \u03ba\u03b1\u03b9 in vivo \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2. \u0398\u03b1 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b4\u03b9\u03c0\u03bb\u03ae \u03c4\u03c5\u03c6\u03bb\u03ae \u03ba\u03b1\u03b9 \u03b5\u03bb\u03b5\u03b3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b8\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5 \u03c4\u03c5\u03c7\u03b1\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b7 \u03ba\u03b1\u03c4\u03b1\u03bd\u03bf\u03bc\u03ae \u03ba\u03b1\u03b9 \u03bc\u03b5 \u03c0\u03c1\u03c9\u03c4\u03b1\u03c1\u03c7\u03b9\u03ba\u03cc \u03c3\u03ba\u03bf\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7.<\/p>\n<p style=\"text-align: justify;\"><strong>2.1<\/strong> \u0391\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u03a0\u03c1\u03c9\u03c4\u03bf\u03b3\u03b5\u03bd\u03ce\u03bd \u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd<br \/>\n\u0398\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03b5\u03c0\u03b9\u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03ba\u03ac\u03c4\u03c9\u03b8\u03b9 \u03b4\u03bf\u03ba\u03b9\u03bc\u03b1\u03c3\u03af\u03b5\u03c2.<\/p>\n<p style=\"text-align: justify;\"><strong>2.2<\/strong> \u0391\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7 \u0394\u03b5\u03c5\u03c4\u03b5\u03c1\u03bf\u03b3\u03b5\u03bd\u03ce\u03bd \u0391\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd<br \/>\n\u0398\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b4\u03b9\u03bf\u03c1\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03bf\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c4\u03c9\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03c9\u03c4\u03b5\u03ca\u03bd\u03ce\u03bd (\u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03b5\u03af\u03c2 \u0391\u03b2, Tau \u03ba\u03b1\u03b9 DKK3) \u03c3\u03c4\u03bf\u03bd \u03bf\u03c1\u03cc \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b5\u03b9\u03b4\u03b9\u03ba\u03ce\u03bd ELISA kit [9, 10], \u03ba\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ce\u03bd \u03b4\u03b5\u03b9\u03ba\u03c4\u03ce\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 (IL- 6, TNF-\u03b1) \u03c3\u03c4\u03bf \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd [11], \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c3\u03c4\u03bf\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c4\u03b7\u03c2 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2 \u03bc\u03b5 \u03c4\u03bf \u03c4\u03bf DiaSys Cholesterol FS kit.<\/p>\n<p style=\"text-align: justify;\"><strong>3.<\/strong> <strong>\u03a0\u03b1\u03c1\u03b1\u03c3\u03ba\u03b5\u03c5\u03ae \u03c6\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u0389\u03c0\u03b9\u03b1 \u039d\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03bd\u03cc\u03c3\u03bf Alzheimer\u2019s<\/strong><br \/>\n\u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03c9\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5\u03bb\u03b5\u03c4\u03ce\u03bd \u03b8\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c6\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03b3\u03b9\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u0389\u03c0\u03b9\u03b1 \u039d\u03bf\u03b7\u03c4\u03b9\u03ba\u03ae \u0394\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03ba\u03b1\u03b9 \u03bd\u03cc\u03c3\u03bf Alzheimer\u2019s.<\/p>\n<p style=\"text-align: justify;\"><strong>3.1<\/strong> \u039c\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03c1\u03bf-\u03bc\u03bf\u03c1\u03c6\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03bf\u03c2<br \/>\n\u0398\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03b7 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03c9\u03bd \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd, \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bf\u03cd\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03b5\u03ba\u03b4\u03cc\u03c7\u03c9\u03bd, \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03c0\u03c1\u03bf\u03c4\u03b1\u03b8\u03bf\u03cd\u03bd \u03b3\u03b9\u03b1 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd. \u0397 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b8\u03b1 \u03b5\u03bb\u03b5\u03b3\u03c7\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b1\u03bd\u03b1\u03bb\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c6\u03c5\u03c3\u03b9\u03ba\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ce\u03bd \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b5\u03ba\u03b4\u03cc\u03c7\u03c9\u03bd, \u03bc\u03b5 \u03c3\u03ba\u03bf\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03bd\u03af\u03c7\u03bd\u03b5\u03c5\u03c3\u03b7 \u03c0\u03b1\u03c1\u03b1\u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03c9\u03bd \u03bc\u03b5 \u03b1\u03bd\u03b1\u03bb\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ad\u03c2 (HPLC, IR, Specific Optical Rotation). \u0398\u03b1 \u03bf\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03c0\u03c1\u03bf\u03c4\u03b5\u03b9\u03bd\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03c3\u03c5\u03bd\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b3\u03b9\u03b1 \u03c4o \u03c5\u03c0\u03cc \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf-\u03bc\u03bf\u03c1\u03c6\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03b3\u03bf\u03c1\u03ac\u03c2.<\/p>\n<p style=\"text-align: justify;\"><strong>3.2<\/strong> \u039c\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bc\u03bf\u03c1\u03c6\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03bf\u03c2<br \/>\n\u03a4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf-\u03bc\u03bf\u03c1\u03c6\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03b8\u03b1 \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c3\u03c5\u03bd\u03b8\u03ad\u03c3\u03b5\u03c9\u03bd, \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03ac\u03c4\u03c9 \u03ba\u03c1\u03b9\u03c4\u03ae\u03c1\u03b9\u03b1:<br \/>\n\u2022 \u03a4\u03b1 \u03b5\u03ba\u03c7\u03c5\u03bb\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03ad\u03ba\u03b4\u03bf\u03c7\u03b1 \u03c3\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ac \u03bc\u03b5\u03c4\u03b1\u03be\u03cd \u03c4\u03bf\u03c5\u03c2.<br \/>\n\u2022 \u0398\u03b1 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03b5\u03af \u03b7 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03b7 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03ae \u03bc\u03bf\u03c1\u03c6\u03ae, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c6\u03cd\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03c9\u03bd \u03b5\u03ba\u03c7\u03c5\u03bb\u03b9\u03c3\u03bc\u03ac\u03c4\u03c9\u03bd, \u03c4\u03bf \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03c3\u03c7\u03ae\u03bc\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b7\u03bc\u03b5\u03c1\u03ae\u03c3\u03b9\u03b1\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03cd\u03ba\u03bf\u03bb\u03bf.<br \/>\n\u03c3\u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b1\u03c0\u03cc \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2, \u03bc\u03b5 \u03b5\u03bd\u03b4\u03b5\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b4\u03c5\u03c3\u03ba\u03bf\u03bb\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03ac\u03c0\u03bf\u03c3\u03b7.<br \/>\n\u2022 \u0398\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c7\u03b8\u03bf\u03cd\u03bd \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03c4\u03c1\u03b5\u03b9\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03bd\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03bb\u03b1\u03c7\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03bd\u03b1 \u03bc\u03b7\u03bd \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03ba\u03c4\u03cc \u03ba\u03b1\u03b9 \u03b5\u03bc\u03c0\u03bf\u03c1\u03b9\u03ba\u03ac \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd \u03bc\u03b5 \u03c4\u03b7\u03bd \u03bf\u03bb\u03bf\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03ad\u03c1\u03b3\u03bf\u03c5.<br \/>\n\u2022 \u039a\u03ac\u03c0\u03bf\u03b9\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03c3\u03c5\u03bd\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b8\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b9\u03bf \u00ab\u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2\u00bb, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03af\u03b3\u03bf\u03c5\u03c1\u03bf \u03cc\u03c4\u03b9 \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03bc\u03b9\u03b1 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03b8\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03c6\u03c5\u03c3\u03b9\u03ba\u03bf\u03c7\u03b7\u03bc\u03b9\u03ba\u03ad\u03c2 \u03b9\u03b4\u03b9\u03cc\u03c4\u03b7\u03c4\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03cc \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd, \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03b9\u03c3\u03c4\u03b5\u03af \u03ba\u03b1\u03c4\u03ac \u03c4\u03bf \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03bd \u03ae \u03cd\u03c0\u03b1\u03c1\u03be\u03b7 \u03b5\u03bc\u03c0\u03bf\u03c1\u03b9\u03ba\u03ac \u03b1\u03be\u03b9\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b9\u03bc\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03bf\u03c2 \u03c3\u03b5 \u03c0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03bf \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03b5\u03c2 \u03c3\u03c5\u03bd\u03b8\u03ad\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b7 \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03b5\u03af\u03c2.<\/p>\n<p style=\"text-align: justify;\"><strong>3.3<\/strong> \u03a0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03c3\u03b5 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ba\u03bb\u03af\u03bc\u03b1\u03ba\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bb\u03bf\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03c4\u03af\u03b4\u03b5\u03c2<br \/>\n\u039f\u03b9 \u03b5\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c6\u03cc\u03c1\u03bc\u03bf\u03c5\u03bb\u03b5\u03c2 \u03b8\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c7\u03b8\u03bf\u03cd\u03bd \u03c3\u03b5 \u03bc\u03b5\u03b3\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03ba\u03bb\u03af\u03bc\u03b1\u03ba\u03b1 \u03bc\u03b5 \u03c3\u03ba\u03bf\u03c0\u03cc \u03c4\u03bf\u03bd \u03ad\u03b3\u03ba\u03b1\u03b9\u03c1\u03bf \u03b5\u03bd\u03c4\u03bf\u03c0\u03b9\u03c3\u03bc\u03cc \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03c0\u03c1\u03b9\u03bd \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03c0\u03b9\u03bb\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03c1\u03c4\u03af\u03b4\u03c9\u03bd. \u0398\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03b5\u03c0\u03af\u03c3\u03b7\u03c2, \u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2, \u03b8\u03b1 \u03ba\u03b1\u03b8\u03bf\u03c1\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03bf\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03bc\u03b5\u03c4\u03c1\u03bf\u03b9 \u03c4\u03b7\u03c2 \u03ba\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ae\u03c2 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03c4\u03b5\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03c0\u03c1\u03bf\u03b4\u03b9\u03b1\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b5\u03bb\u03ad\u03b3\u03c7\u03bf\u03c5\u03c2 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae (in-process controls).<\/p>\n<p style=\"text-align: justify;\"><strong>3.4<\/strong> \u039c\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ce\u03bd \u03c4\u03bf\u03c5 \u03c4\u03b5\u03bb\u03b9\u03ba\u03bf\u03cd \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7\u03c2 \u03b1\u03b3\u03bf\u03c1\u03ac\u03c2 &amp; \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1 \u03b4\u03b9\u03ba\u03b1\u03b9\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03b5\u03c5\u03c1\u03b5\u03c3\u03b9\u03c4\u03b5\u03c7\u03bd\u03af\u03b1\u03c2<br \/>\n\u03a4\u03bf \u03c4\u03b5\u03bb\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd \u03b8\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03b3\u03b9\u03b1 \u03b5\u03bc\u03c0\u03bf\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03ae\u03b4\u03b7 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03bc\u03bf\u03cd. \u0397 \u03b1\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac \u03b1\u03c5\u03c4\u03ae \u03b8\u03b1 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b7\u03b8\u03b5\u03af \u03c3\u03c4\u03bf \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc (business plans) \u03c4\u03c9\u03bd \u03c4\u03bc\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd business development \u03ba\u03b1\u03b9 marketing \u03c4\u03b7\u03c2 \u03b5\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1\u03c2. \u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 \u03bc\u03bf\u03c1\u03c6\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03c9\u03bd, \u03b8\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b9\u03c9\u03c7\u03b8\u03b5\u03af \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03bf\u03c7\u03cd\u03c1\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03bf\u03c1\u03c6\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03c9\u03bd \u03b1\u03c5\u03c4\u03ce\u03bd \u03bc\u03ad\u03c3\u03b1 \u03b1\u03c0\u03cc \u03b4\u03af\u03c0\u03bb\u03c9\u03bc\u03b1 \u03b5\u03c5\u03c1\u03b5\u03c3\u03b9\u03c4\u03b5\u03c7\u03bd\u03af\u03b1\u03c2.<\/p>\n<p style=\"text-align: justify;\"><strong>4. \u0394\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03b4\u03b9\u03b1\u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b2\u03ac\u03c3\u03b7\u03c2 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b1 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ac \u03c6\u03c5\u03c4\u03ac<\/strong><br \/>\n\u0391\u03c1\u03c7\u03b9\u03ba\u03ac \u03b8\u03b1 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03b8\u03b5\u03af \u03b7 \u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 (state-of-the-art) \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b1 \u03b4\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b1 \u03c3\u03c4\u03bf\u03b9\u03c7\u03b5\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b9\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b5\u03c2, \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c4\u03cc\u03c7\u03bf\u03c5\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03cc\u03c4\u03b1\u03c3\u03b7\u03c2. \u0397 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c4\u03b7\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c4\u03ac\u03b8\u03bc\u03b9\u03c3\u03b7\u03c2 \u03b8\u03b1 \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03b5\u03b9 \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03be\u03b1\u03c7\u03b8\u03bf\u03cd\u03bd \u03bf\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ad\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2 (functional and non-functional requirements) \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b2\u03ac\u03c3\u03b7 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03bf \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03bf \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc \u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1.<br \/>\n\u03a3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03b8\u03b1 \u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03c3\u03b5\u03b9 \u03bf \u03c4\u03b5\u03c7\u03bd\u03b9\u03ba\u03cc\u03c2 \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c4\u03bf\u03c5 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03b1\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 mobile \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae\u03c2, \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03c4\u03bf \u03c3\u03c5\u03bd\u03bf\u03b4\u03b5\u03cd\u03b5\u03b9.<\/p>\n<\/div><\/div><\/div><\/div>[vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row full_width=&#8221;container-stretch&#8221; agro_row_prepad=&#8221;ptb-140&#8243; css=&#8221;.vc_custom_1549793979536{padding-bottom: 124px !important;}&#8221; agro_md_css=&#8221;.vc_custom_1549793979547{padding-bottom: 84px !important;}&#8221; el_class=&#8221;section section&#8211;dark-bg&#8221; agro_sm_css=&#8221;.vc_custom_1549793979550{padding-bottom: 54px !important;}&#8221;][vc_column el_class=&#8221;section-heading&#8211;white&#8221;]<div class=\"section-heading section-heading--center item_6a06f169dc7dc\" data-res-css=\"     \" data-aos=\"fade\"><h2 class=\"__title\">\u03a6\u039f\u03a1\u039c\u0391 <span>\u0395\u03a0\u0399\u039a\u039f\u0399\u039d\u03a9\u039d\u0399\u0391\u03a3<\/span><\/h2><p>\u0393\u03b9\u03b1 \u03bf\u03c0\u03bf\u03b9\u03b1\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b1 \u03bc\u03b7 \u03b4\u03b9\u03c3\u03c4\u03ac\u03c3\u03b5\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03ae\u03c3\u03b5\u03c4\u03b5 \u03bc\u03b1\u03b6\u03af \u03bc\u03b1\u03c2.<\/p><\/div>\n<div class=\"wpcf7 no-js\" id=\"wpcf7-f12-o1\" lang=\"en-US\" dir=\"ltr\" data-wpcf7-id=\"12\">\n<div class=\"screen-reader-response\"><p role=\"status\" aria-live=\"polite\" aria-atomic=\"true\"><\/p> <ul><\/ul><\/div>\n<form action=\"\/index.php?rest_route=%2Fwp%2Fv2%2Fpages%2F1097#wpcf7-f12-o1\" method=\"post\" class=\"wpcf7-form init\" aria-label=\"Contact form\" novalidate=\"novalidate\" data-status=\"init\">\n<fieldset class=\"hidden-fields-container\"><input type=\"hidden\" name=\"_wpcf7\" value=\"12\" \/><input type=\"hidden\" name=\"_wpcf7_version\" value=\"6.1.5\" \/><input type=\"hidden\" name=\"_wpcf7_locale\" value=\"en_US\" \/><input type=\"hidden\" name=\"_wpcf7_unit_tag\" value=\"wpcf7-f12-o1\" \/><input type=\"hidden\" name=\"_wpcf7_container_post\" value=\"0\" \/><input type=\"hidden\" name=\"_wpcf7_posted_data_hash\" value=\"\" \/><input type=\"hidden\" name=\"_wpcf7_recaptcha_response\" value=\"\" \/>\n<\/fieldset>\n<div class=\"contact-form js-contact-form\" data-aos=\"fade\">\n\t<div class=\"row\">\n\t\t<div class=\"col-12 col-md-6\">\n\t\t\t<div class=\"input-wrp\">\n\t\t\t\t<p><span class=\"wpcf7-form-control-wrap\" data-name=\"text-787\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required textfield\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"\u038c\u03bd\u03bf\u03bc\u03b1\" value=\"\" type=\"text\" name=\"text-787\" \/><\/span>\n\t\t\t\t<\/p>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"col-12 col-md-6\">\n\t\t\t<div class=\"input-wrp\">\n\t\t\t\t<p><span class=\"wpcf7-form-control-wrap\" data-name=\"text-787\"><input size=\"40\" maxlength=\"400\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required textfield\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"E-mail\" value=\"\" type=\"text\" name=\"text-787\" \/><\/span>\n\t\t\t\t<\/p>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\t<div class=\"input-wrp\">\n\t\t<p><span class=\"wpcf7-form-control-wrap\" data-name=\"textarea-212\"><textarea cols=\"10\" rows=\"2\" maxlength=\"2000\" class=\"wpcf7-form-control wpcf7-textarea wpcf7-validates-as-required textfield\" aria-required=\"true\" aria-invalid=\"false\" placeholder=\"\u03a3\u03c7\u03cc\u03bb\u03b9\u03b1\" name=\"textarea-212\"><\/textarea><\/span>\n\t\t<\/p>\n\t<\/div>\n<span class=\"wpcf7-form-control-wrap recaptcha\" data-name=\"recaptcha\"><span data-sitekey=\"6Ld11KofAAAAAAP3Wq9GxwwtIVpOLjrq1TXAW260\" class=\"wpcf7-form-control wpcf7-recaptcha g-recaptcha\"><\/span>\r\n<noscript>\r\n\t<div class=\"grecaptcha-noscript\">\r\n\t\t<iframe loading=\"lazy\" src=\"https:\/\/www.google.com\/recaptcha\/api\/fallback?k=6Ld11KofAAAAAAP3Wq9GxwwtIVpOLjrq1TXAW260\" frameborder=\"0\" scrolling=\"no\" width=\"310\" height=\"430\">\r\n\t\t<\/iframe>\r\n\t\t<textarea name=\"g-recaptcha-response\" rows=\"3\" cols=\"40\" placeholder=\"reCaptcha Response Here\">\r\n\t\t<\/textarea>\r\n\t<\/div>\r\n<\/noscript>\r\n<\/span>\n\t<p><p class=\"cf7ascaptcha\"><input name=\"cf7as_hdn_cpthaval1\" id=\"cf7as_hdn_cpthaval1\" type=\"hidden\" value=\"7\" \/><input name=\"cf7as_hdn_cpthaval2\" id=\"cf7as_hdn_cpthaval2\" type=\"hidden\" value=\"4\" \/><input name=\"cf7as_hdn_cpthaaction\" id=\"cf7as_hdn_cpthaaction\" type=\"hidden\" value=\"+\" \/>What is  <span class=\"cf7as-firstAct\">4<\/span> +<span class=\"cf7as-firstAct\"> 7<\/span> <br><span class=\"wpcf7-form-control-wrap cf7as-captchcode\" data-name=\"cf7as-captchcode\"> <input type=\"text\" aria-invalid=\"false\" aria-required=\"true\" class=\"wpcf7-form-control wpcf7-text wpcf7-validates-as-required\" size=\"5\" value=\"\" name=\"cf7as-captchcode\" placeholder=\"Type your answer\" style=\"width:200px;margin-bottom:10px;\" oninput=\"this.value = this.value.replace(\/[^0-9.]\/g, '').replace(\/(\\..*)\\.\/g, '$1');\"><\/span><input type=\"hidden\" name=\"cf7as-zplus\" value=\"\"><\/p><input type=\"hidden\" id=\"cf7as_captcha_nonce\" name=\"cf7as_captcha_nonce\" value=\"c8c20bf247\" \/><input type=\"hidden\" name=\"_wp_http_referer\" value=\"\/index.php?rest_route=%2Fwp%2Fv2%2Fpages%2F1097\" \/><br \/>\n<input class=\"wpcf7-form-control wpcf7-submit has-spinner custom-btn custom-btn--medium custom-btn--style-3 wide\" type=\"submit\" value=\"\u0391\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03b7\" \/>\n\t<\/p>\n<\/div><div class=\"wpcf7-response-output\" aria-hidden=\"true\"><\/div>\n<\/form>\n<\/div>\n[\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row full_width=&#8221;container-null&#8221;][vc_column agro_disable_column=&#8221;yes&#8221;][\/vc_column][\/vc_row][vc_row full_width=&#8221;container-null&#8221;][vc_column agro_disable_column=&#8221;yes&#8221;][vc_empty_space height=&#8221;50px&#8221;][\/vc_column][\/vc_row][vc_row full_width=&#8221;container-stretch&#8221; agro_row_prepad=&#8221;ptb-140&#8243; css=&#8221;.vc_custom_1549793979536{padding-bottom: 124px !important;}&#8221; agro_md_css=&#8221;.vc_custom_1549793979547{padding-bottom: 84px !important;}&#8221; el_class=&#8221;section section&#8211;dark-bg&#8221; agro_sm_css=&#8221;.vc_custom_1549793979550{padding-bottom: 54px !important;}&#8221;][vc_column el_class=&#8221;section-heading&#8211;white&#8221;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1185,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"custom-page.php","meta":{"footnotes":""},"class_list":["post-1097","page","type-page","status-publish","hentry"," nt-post-class"],"_links":{"self":[{"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/pages\/1097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/herbalaid.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1097"}],"version-history":[{"count":28,"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/pages\/1097\/revisions"}],"predecessor-version":[{"id":1482,"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/pages\/1097\/revisions\/1482"}],"up":[{"embeddable":true,"href":"https:\/\/herbalaid.gr\/index.php?rest_route=\/wp\/v2\/pages\/1185"}],"wp:attachment":[{"href":"https:\/\/herbalaid.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}